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Tia Free Acid CAS 66981-73-5

 

Product name:Tianeptine Acid
Appearance:White Powder
CAS:
66981-73-5
MF:C21H25ClN2O4S
EINECS No:614-004-0
Molecular weithgs:436.95
Melting point:129-131°C
Purity:99%
Shelf life:2 years
Storage:Keep in cool dry place.
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Product Details

Product introduction

Cas: 66981-73-5

Appearance: White or almost white microcrystalline powder

MF: C23H29ClN2O4S


Overview: Product description:
Tianeptine is a drug used for treating major depressive episodes (mild, moderate, or severe). It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer (SSRE), opposite to the action of SSRIs. One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors.
Tianeptine also known as stablon, is a drug primarily used in the treatment of Major depressive disorder. It has also been used to treat irritable bowel syndrome and asthma. Tianeptine has antidepressant and anti-anxiety properties.

Tianeptine has a variety of effects on the body, including motivation enhancement, anxiety suppression, cognitive euphoria, focus enhancement, rejuvenation, and cognitive fatigu.

Associated Conditions: Major Depressive Disorder (MDD)

Application: Tia free acid is tricyclic antidepressants that have antidepressant effects by acting on the serotonin system. In animal experiments, they can increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate their recovery after inhibition of function. It can increase the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus

Other chemical names: Coaxil, Stablon,

7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)-amino]heptanoic acid s,s-dioxide


Certificate of analysia

TEST ITEM

SPECIFICATION

RESULT

Appearance

White or almost white microcrystalline powder

White powder

Solubility

Insoluble in the water and methanol

Complies

Identification

Should comply

Complies

Related substance

Individual impurity: Not more than0.1%

0.06%

Total impurities: Not more than 0.5% 0.13%

Residue on ignation

Not more than 0.2%

0.02%

Loss on drying

Not more than 1.0%

0.09%

Heavy metal

Not more than 20ppm

< 20ppm

Assay (on anhydrous basis)

Not less than 99.0%

99.35%

Conclusion : Conform to per enterprise standard


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