Lapatinib ditosylate powder cas 388082-78-8 is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity.

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Product Details

Product introduction：

CAS: 388082-78-8

MF: C₄₁H₄₀ClFN₄O₁₁S₃

Molecular Weight: 925.5 g/mol

Applications: Antimalarial drug, anti-cancer drug

Description: Lapatinib ditosylate powder cas 388082-78-8 is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity.

Application: Lapatinib ditosylate powder cas 388082-78-8 reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.

Certificate of analysis

Test items	Standards	Results
Appearance	Yellow powder	Conforms
Identification	IR	Conforms
Melting point	242-249℃	245.5-247.6℃
Total impurities	≤1.0％	0.6%
Loss on drying	≤1.0％	0.2％
Heavy metals	≤20ppm	Conforms
Assay	≥99.0%	99.4%

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